Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer
NCT07369986 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-01-27
Summary
Efficacy evaluate of iparomlimab and tuvonralimab (a PD-1/CTLA-4 bispecific antibody) in patients with surgically resectable dMMR endometrial cancer.
Conditions
- Endometrial Cancer
- Immunotherapy
- Mismatch Repair Deficiency
Interventions
- DRUG
-
Iparomlimab and Tuvonralimab (QL1706)
Iparomlimab and Tuvonralimab as a strategy to facilitate non-surgical management in women with surgically completely resectable dMMR endometrial cancer.
Sponsors & Collaborators
-
Women's Hospital School Of Medicine Zhejiang University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-01
- Primary Completion
- 2027-12-31
- Completion
- 2028-12-31
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