Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver
NCT07364474 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2026-03-11
Summary
This study seeks to better understand the liver's immune response to receiving chemotherapy agent melphalan through Percutaneous Hepatic Perfusion (PHP) for patients with Uveal Melanoma that has metastasized to the liver.
Conditions
Interventions
- DRUG
-
Melphalan through Percutaneous Hepatic Perfusion
Melphalan through Percutaneous Hepatic Perfusion will be received as standard of care,
Sponsors & Collaborators
-
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Eric Wehrenberg-Klee, MD · Massachusetts General Hospital
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-01-27
- Primary Completion
- 2027-12-31
- Completion
- 2028-09-30
Countries
- United States
Study Locations
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