Comparison of Eohilia With Dupixent on Esophagus Diameter in Patients With Eosinophilic Esophagitis.
NCT07358234 · Status: ENROLLING_BY_INVITATION · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2026-05-04
Summary
The purpose of this study is to compare Eosinophilic Esophagitis treatments Eohilia with Dupixent in their effects on diameter and scarring of the esophagus.
Conditions
- Eosinophilic Esophagitis (EoE)
Interventions
- DRUG
-
Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]
300 mg weekly injection
- DRUG
-
budesonide oral suspension
2mg twice daily
Sponsors & Collaborators
-
Vanderbilt University Medical Center
collaborator OTHER - lead OTHER
Principal Investigators
-
Diana Snyder, M.D. · Mayo Clinic
-
Jennifer Horsley-Silva, M.D. · Mayo Clinic
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-02-04
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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