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Auricular Acupressure Combined With Adapalene for the Treatment of Acne Vulgaris

NCT07348978 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2026-01-16

No results posted yet for this study

Summary

Acne vulgaris is a common chronic inflammatory skin condition that can significantly affect quality of life. Standard treatments such as topical retinoids are effective but may not fully control symptoms in all patients.

This study evaluated the effectiveness of auricular acupressure combined with topical 0.1% adapalene compared with topical 0.1% adapalene alone in patients with acne vulgaris. Auricular acupressure is a non-invasive traditional medicine technique that may help regulate inflammatory responses and improve skin conditions.

The objective of this study was to determine whether the combination therapy provides greater improvement in acne severity and clinical outcomes than standard topical treatment alone.

Conditions

  • Acne Vulgaris

Interventions

OTHER

Auricular Acupressure

Auricular acupressure was performed by applying pressure to specific auricular points according to traditional medicine principles. The intervention was administered as an adjunctive therapy in combination with topical adapalene.

DRUG

Adapalene 0.1% Gel

Topical adapalene 0.1% was applied to affected areas once daily as standard treatment for acne vulgaris.

Sponsors & Collaborators

  • University of Medicine and Pharmacy at Ho Chi Minh City

    lead OTHER

Principal Investigators

  • Bay Thi Nguyen, PhD · University of Medicine and Pharmacy at Ho Chi Minh City

  • Huy Chung Ly · University of Medicine and Pharmacy at Ho Chi Minh City

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-01
Primary Completion
2025-06-30
Completion
2025-11-10

Countries

  • Vietnam

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07348978 on ClinicalTrials.gov