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The Effect of Dual-target tACS Combined With Speech Training on Repetition Disorder After Stroke

NCT07347327 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2026-01-22

No results posted yet for this study

Summary

This clinical trial aims to study whether dual-target transcranial alternating current stimulation (tACS) applied to the auditory and motor brain region can improve repetition disorder in people with stroke, and to evaluate the safety of tACS. The main goals are to answer the following questions:

1. Can dual-tACS stimulation of the auditory and motor brain area improve repetition functions in people with aphasia after stroke?
2. Can it improve the integration of auditory information and speech motor control during communication?

Researchers will compare the effects of real tACS versus sham (placebo) stimulation to see if real stimulation leads to better outcomes in aphasia patients.

Participants will:

1. Receive one extra 20-minute session of either real or sham tACS each day for 10 days
2. Attend clinic visits before and after 10-days stimulation for clinical assessments(WAB) and fNIRS recording related brain activity

Conditions

  • Aphasia

Interventions

BEHAVIORAL

speech training

speech training(especially repetition training) synchronized with tACS stimulation

OTHER

real tACS

dual-target tACS on auditory and motor brain area at a frequency of 8 Hz,with individualized current intensity, delivered for 20 minutes.

OTHER

sham tACS

except for turning down the current intensity to zero during the 20-minute period, all other parameters are identical to those in real group.

Sponsors & Collaborators

  • Ke Dong, MD

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2025-12-26
Completion
2025-12-29

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07347327 on ClinicalTrials.gov