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Comparison of the Ultrasonic Cardiac Output Monitor and Echocardiography for Hemodynamic Assessment in Pediatric Anesthesia

NCT07342842 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 57

Last updated 2026-01-15

No results posted yet for this study

Summary

This prospective observational pilot study evaluates agreement between Ultrasound Cardiac Output Monitor (USCOM) measurements and transthoracic echocardiography-derived hemodynamic parameters in pediatric patients under standardized general anesthesia prior to surgical incision. Under stable hemodynamic and ventilatory conditions, suprasternal Doppler-derived velocity time integral (VTI), stroke volume (SV), cardiac output (CO), stroke volume variation (SVV), and aortic valve area (AVA) are obtained sequentially with USCOM and echocardiography within a short time window without changes in ventilation, anesthetic depth, positioning, fluid therapy, or vasoactive support. Agreement is assessed using correlation and Bland-Altman analyses.

Conditions

  • USCOM
  • Echocardiography
  • Echocardiography Guided Fluid Management

Interventions

OTHER

USCOM

Ultrasound cardiac output monitoring is performed using a suprasternal approach to obtain spectral Doppler signals from the ascending aorta. After anesthesia induction and stabilization, the probe is positioned at the suprasternal notch to acquire optimal Doppler waveforms. Velocity time integral (VTI), stroke volume (SV), cardiac output (CO), stroke volume variation (SVV), systemic vascular resistance (SVR), and device-calculated aortic valve area (AVA) are recorded using the manufacturer's algorithm. Only high-quality Doppler envelopes are accepted, and measurements are repeated if artifacts or poor signal quality are present. All parameters are obtained consecutively under unchanged ventilatory and hemodynamic conditions.

OTHER

Echocardiography

Transthoracic echocardiography is performed immediately after USCOM measurements under unchanged anesthetic depth, ventilator settings, and patient positioning. Using a pediatric probe, suprasternal Doppler recordings are obtained from the ascending aorta, with the Doppler cursor aligned as parallel as possible to blood flow; angle correction is applied when necessary. Velocity time integral (VTI) is measured from the largest and most clearly defined spectral Doppler envelope. The aortic annulus diameter is obtained from the parasternal long-axis view during midsystole, and aortic valve area is calculated. Stroke volume is derived as aortic valve area × VTI, and cardiac output is calculated as stroke volume × heart rate. Inspiratory and expiratory VTI values are recorded to determine respiratory variation and calculate stroke volume variation. Each parameter is measured three times and averaged for analysis.

Sponsors & Collaborators

  • Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

    lead OTHER

Eligibility

Min Age
6 Months
Max Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2022-03-01
Completion
2022-03-15

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07342842 on ClinicalTrials.gov