Additional Effects of Sensory Integration Along With Focused Regimen Exercises on Kinaesthesia & Proprioception in Diabetic Peripheral Neuropathy.

Summary

This study aims to evaluate Additional Effects of sensory integration along with focused regimen exercises on kinaesthesia \& proprioception in Diabetic peripheral neuropathy Peripheral neuropathy a Condition occur when the nerves outside the brain and spinal cord are damaged. It affects the upper and lower extremity. The estimated prevalence of peripheral neuropathy in patients with diabetes in Pakistan is around 43%. The condition is more common in those who have poorly controlled diabetes. Signs and symptoms include Numbness, tingling, Pain, which may be burning, stabbing or shooting, unusual touch-based sensations (dysesthesia), Muscle weakness, Total or partial loss of sensation in feet, like not feeling pain from foot injuries, loss of position and movement sense.

Kinaesthesia and proprioception are defined as awareness of the position and movement of the body parts by sensory organs (proprioceptors) in the muscles and joints. Uncoordinated movement, clumsiness, poor postural control are common symptoms. Multiple treatment options are available for training kinaesthesia and proprioception impairments in peripheral neuropathy including use of electrotherapeutic agents, proprioception exercises, sensory integration, and focused regimen exercises. Current study will be RCT on 40 participants recruited on the basis of inclusion criteria which are Diagnosed as Type 2 Diabetic peripheral neuropathy (DPN) by physician in the age group of 45-65 Years in Both genders with type 2 Diabetes. Patients with moderate neuropathy according to Michigan nephropathy screening tool and having the ability to walk with or without assistance. Participants will be randomly and equally divided into two groups; group A will be receiving focused regimen exercises and group B will be receiving both sensory integration exercises along with focused regimen exercises.

The treatment will be given for 45min, 3 days a week for total of 8 weeks. The assessment will be conducted at baseline by (Michigan neuropathy screening tool, Brief kinaesthesia test (BKT), Modified Clinical Test of Sensory Interaction for balance (mCTSIB), Norfolk quality of life for diabetic neuropathy), and final assessment will be conducted after 8 weeks of treatment.

Conditions

• Diabetic Neuropathy
• Proprioception

Interventions

PROCEDURE

Sensory integration and focused regimen

3 sessions/week 1-2 weeks : textured ball and brush on feet. (3-5 min/foot). Ankle circles, toe scrunches.10 reps x 2 sets, Tens 10min, 2 sets calf raises (10 reps). resistance band (10 reps x 2 sets). 3-4 weeks: Shift weight side-to-side and forward-backward on foam pad (10 reps x 2 sets). calf raises, progressing to single-leg calf raises 10 reps x 2 sets. Step-ups: Step up and down 10 reps x 2 sets. Standing on board 30 sec. Open. 5-6 weeks: Tandem walking. Tens 8min. Balance on one leg while catching a ball (20-30 sec). barefoot walking (grass, gravel).Tens 6min. Double-leg squats10 reps x 1 set. side-to-side and forward-backward stepping 10 reps x 2 sets. 7-8 weeks: Walk over \& around obstacles. Balance wobble board for 30 sec-2 reps. Balance barefoot on uneven terrain while catching a ball. Weighted calf raises 10 reps x 3 sets. Standing on firm surface for 30 sec. Eyes close, Single-leg stance 10 reps x 3 sets

PROCEDURE

Focused Regimen Exercise

3 sessions/week 1-2 weeks Perform 2 sets of calf raises (10 reps). Use a resistance band (green colour) 10 reps x 2 sets. 3-4 weeks: calf raises, progressing to single-leg calf raises. 10 reps x 2 sets Step-ups: Step up and down on a low step 10 reps x 2 sets. Standing on board for 30 sec. Open. 5-6 weeks :Double-leg squats10 reps x 1 set. Perform side-to-side and forward-backward stepping 10 reps x 2 sets Weighted . 7-8 weeks: calf raises 10 reps x 3 sets. Standing on firm surface for 30 sec. Eyes close, Single-leg stance on firm ground10 reps x 3 sets

Sponsors & Collaborators

• Foundation University Islamabad

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

45 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-09-15

Primary Completion

2025-10-26

Completion

2025-12-20

Countries

• Pakistan

Study Locations