MedTrace Logo

Predictive Score for the Success of Discontinuation of Renal Replacement Therapy (RRT) in Intensive Care

NCT07317362 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5976

Last updated 2026-01-05

No results posted yet for this study

Summary

The goal of this observational study is to evaluate when renal replacement therapy (RRT) can be safely discontinued in intensive care unit (ICU) patients with acute kidney injury (AKI). The main question it aims to answer is:

Can the UNDERSCORE predictive score accurately identify ICU patients with AKI who can successfully stop RRT without needing restart or experiencing early death?

Using routinely collected clinical data from the AP-HP Health Data Warehouse, the study will follow ICU patients with AKI treated with RRT to assess whether the UNDERSCORE score predicts successful RRT discontinuation within 7 days.

Conditions

  • D012139
  • D003924

Interventions

OTHER

Discontinuation of renal replacement therapy

Discontinuation of renal replacement therapy is defined as the absence of RRT resumption within 3 days for intermittent RRT, and as definitive cessation for continuous RRT.

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Khalil Chaibi, MD · Medecine intensive-reanimation. Service de Réanimation médico-chirurgicale, Hôpital Avicenne, APHP, Bobigny (France)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-11-19
Primary Completion
2025-12-15
Completion
2025-12-15

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07317362 on ClinicalTrials.gov