Study of Cabozantinib in Participants With Neuroendocrine Tumors Who Have Already Received Prior Treatment
NCT07314164 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2026-04-30
Summary
This study will assess how well cabozantinib works and how safe it is in adults with a type of cancer called neuroendocrine tumors (NETs).
These tumors can appear in all parts of the body. All participants in this study have already received at least one treatment that affects the whole body to help manage their cancer, but their disease has continued to grow.
The study will take place in regular hospitals and clinics in Germany and Austria.
It will follow about 150 participants who are taking cabozantinib as part of their usual care. Doctors will collect information from routine medical visits, tests, and scans to see how the cancer responds to treatment and how long participants stay on cabozantinib. They will also look at side effects and how the treatment affects participants' quality of life.
This is an observational study, which means that no extra tests or procedures will be done beyond what is normally used to care for participants with this condition.
Conditions
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Ipsen Medical Director · Ipsen
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-17
- Primary Completion
- 2027-10-31
- Completion
- 2028-12-31
Countries
- Austria
- Germany
Study Locations
More Related Trials
-
Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma
NCT04164979 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM)
NCT04893785 ·Status: RECRUITING ·Phase: PHASE2
-
Evaluating the Safety and Efficacy of SB Injection in Patients With Advanced or Metastatic Gastric Cancer
NCT01305993 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase II Study to Evaluate the Effects of Sequential Therapy With the Anti c-MET/VEGFR Tyrosine Kinase Inhibitor (TKI), Cabozantinib, Followed by an Anti-PD-1 Antibody (Nivolumab) in Patients With Advanced HCC Who Progressed on First-line Therapy
NCT05039736 ·Status: WITHDRAWN ·Phase: PHASE2
-
Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine Tumors
NCT04079712 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Neoadjuvant Immunotherapy Plus Chemotherapy in Borrmann Type 4 and Large Type 3 Gastric Cancer
NCT06451211 ·Status: RECRUITING ·Phase: PHASE2
-
Cabozantinib and Lanreotide as Treatment for Gastroenteropancreatic Neuroendocrine Tumors
NCT05048901 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of Nivolumab Plus Chemotherapy in First Line Treatment of Adult Participants With Advanced or Metastatic Gastric Cancer
NCT05165264 ·Status: ACTIVE_NOT_RECRUITING
-
The Safety and Efficacy of Neoadjuvant Immunochemotherapy Followed by Laparoscopic Gastrectomy for Gastric Cancer
NCT06235164 ·Status: ACTIVE_NOT_RECRUITING
-
Cabozantinib in High Grade Neuroendocrine Neoplasms
NCT04412629 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study
NCT05753306 ·Status: RECRUITING ·Phase: PHASE2
-
68Ga-OPS202 Study for Diagnostic Imaging of GEP NET
NCT02162446 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Transarterial Chemoembolization With Lipiodol in the Treatment of Initial Unresectable Gastric Cancer (GC)
NCT05361161 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Non-Interventional Study of Xeloda (Capecitabine) in Patients With Gastric Cancer
NCT02274376 ·Status: COMPLETED
-
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
NCT07043400 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of Capecitabine (Xeloda) in Participants With Advanced or Metastatic Gastric Cancer
NCT02563054 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Compare Capecitabine Combined With Dacarbazine(CAPDTIC) Versus Capecitabine Combined Temozolomide(CAPTEM) in Advanced and Metastatic Gastrointestinal Pancreatic and Esophageal Neuroendocrine Tumor
NCT03279601 ·Status: UNKNOWN ·Phase: PHASE2
-
Bevacizumab Plus Somatostatin Analogue and Metronomic Capecitabine in Patients With Advanced Neuroendocrine Tumors
NCT01203306 ·Status: UNKNOWN ·Phase: PHASE2
-
Randomized Multicenter Study Comparing Docetaxel Plus Cisplatin and 5-FU to Cisplatin Plus 5-FU in Advanced Gastric Cancer
NCT00290966 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France
NCT06504615 ·Status: ACTIVE_NOT_RECRUITING
-
Treatment of Locally Advanced or Metastatic Transitional Cell Carcinoma With Cabazitaxel
NCT01668459 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
TEMCAP in Grade 3 and Low Ki-67 Gastroenteropancreatic Neuroendocrine Tumors
NCT03079440 ·Status: COMPLETED ·Phase: PHASE2
-
Combination of Capmatinib + Spartalizumab in Advanced Oesogastric Adenocarcinoma
NCT05135845 ·Status: SUSPENDED ·Phase: PHASE2
-
Nab-paclitaxel Plus Camrelizumab and S-1 Conversion Therapy for Gastric Cancer With Positive Exfoliative Cancer Cells
NCT05410847 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of IMU-131(HER-Vaxx) and Chemotherapy Compared to Chemotherapy Only in Patients With HER2 Positive Advanced Gastric Cancer
NCT02795988 ·Status: COMPLETED ·Phase: PHASE1/PHASE2