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Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

NCT07313371 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2026-02-24

No results posted yet for this study

Summary

This is a single-center, randomized intervention study in a volunteer population of patients with cocaine/crack use disorder to evaluate the pharmacological treatment of cocaine/crack craving, comparing the drug clonidine with the active placebo clonazepam.

Conditions

  • Cocaine Use Disorder
  • Crack Abuse or Dependence

Interventions

DRUG

clonidine

Clonidine 0,1 mg bid

DRUG

clonazepam 0,25 mg

clonazepam 0,25 mg bid

Sponsors & Collaborators

  • University of Sao Paulo General Hospital

    lead OTHER

Principal Investigators

  • Dangela Lassi · University of São Paulo General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-28
Primary Completion
2026-07-31
Completion
2027-07-31

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07313371 on ClinicalTrials.gov