A Study of F182112 in the Treatment of Patients With Relapsed or Refractory Multiple Myeloma
NCT07312188 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2025-12-31
Summary
This is a single - arm, multi - cohort, open - label, multi - center Phase II clinical study. It aims to evaluate the efficacy and safety of F182112 combined with different administration regimens in patients with relapsed or refractory multiple myeloma.
Conditions
Interventions
- DRUG
-
F182112+P
F182112 + P
- DRUG
-
F182112+CD38
F182112+CD38
Sponsors & Collaborators
-
Shandong New Time Pharmaceutical Co., LTD
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-07-02
- Primary Completion
- 2028-05-20
- Completion
- 2028-05-20
Countries
- China
Study Locations
More Related Trials
-
A Phase 1/2a Study of Human Anti-CD 38 Antibody MOR03087 (MOR202) in Relapsed/Refractory Multiple Myeloma
NCT01421186 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of the Safety and Pharmacokinetics of MFGR1877S in Patients With Relapsed or Refractory t(4;14)-Positive Multiple Myeloma
NCT01122875 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Treatment for Newly Diagnosed Multiple Myeloma Patients Older Than 65 Years With Sequential Melphalan/Prednisone/Velcade (MPV) Followed by Revlimid/Low Dose Dexamethasone (Rd) Versus Alternating Velcade/Melphalan/Prednisone (MPV) With Revlimid/Low Dose Dexamethasone
NCT01237249 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate the Safety and Efficacy of Anti-CD38 CAR-T in Relapsed or Refractory Multiple Myeloma Patients
NCT03464916 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy Study of An Anti-CD38 Antibody Drug Conjugate in Relapsed or Refractory Multiple Myeloma
NCT05565807 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
All-trans Retinoic Acid in Combination With a KPD Regimen for the Treatment of Refractory/Relapsed Multiple Myeloma
NCT06158412 ·Status: RECRUITING ·Phase: PHASE2
-
This is an Open-label, Single Arm Study to Evaluate the Safety and Tolerability of Treatment With CT0591CP in Patients With Relapsed and/or Refractory Multiple Myeloma.
NCT05486975 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma
NCT05338775 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of QLS32015 in Patients With Recurrent or Refractory Multiple Myeloma
NCT05920876 ·Status: UNKNOWN ·Phase: PHASE1
-
Ph 1b Study to Evaluate GSK2110183 in Combination With Bortezomib and Dexamethasone in Subjects With Multiple Myeloma
NCT01428492 ·Status: COMPLETED ·Phase: PHASE1
-
A Single Agent Study to Evaluate the Overall Response Rate, Safety and Tolerability of Orally Administered Vemurafenib
NCT02115035 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Ph I Study in Adult Patients With Relapsed or Refractory Multiple Myeloma
NCT05027594 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma
NCT05160584 ·Status: RECRUITING
-
Study of the Safety and Pharmacokinetics of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma and Varying Degrees of Renal Function
NCT00721734 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Daratumumab in Japanese Participants With Relapsed or Refractory Multiple Myeloma
NCT02116569 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Fluphenazine in Relapsed or Relapsed-and-Refractory Multiple Myeloma
NCT00821301 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment
NCT04035226 ·Status: COMPLETED
-
Study of the Safety and Efficacy of an Investigational Drug in Adult Patients With Multiple Myeloma
NCT00036140 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Pharmacokinetics and Efficacy Study of Bisthianostat in Refractory or Recurrent Multiple Myeloma Patients
NCT03618602 ·Status: UNKNOWN ·Phase: PHASE1
-
Study to Evaluate the Safety and Efficacy of Pomalidomide Monotherapy in Subjects With Refractory or Relapsed Refractory Multiple Myeloma
NCT01324947 ·Status: COMPLETED ·Phase: PHASE3
-
Multiple Myeloma Patient Registry
NCT03180853 ·Status: TERMINATED
-
Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma
NCT00511238 ·Status: COMPLETED ·Phase: PHASE2
-
Use of Elranatamab in Patients With High-risk Smoldering Multiple Myeloma
NCT06183489 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of JNJ-54767414 (Daratumumab) in Combination With Bortezomib and Dexamethasone (D-Vd) in Japanese Participants With Relapsed or Refractory Multiple Myeloma
NCT02497378 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Dose Determining Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma
NCT00723359 ·Status: COMPLETED ·Phase: PHASE1