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Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial.

NCT07311759 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2025-12-31

No results posted yet for this study

Summary

Our objective is to compare the efficacy and safety of intralesional corticosteroids + fluconazole solution to corticosteroid with an antifungal topical preparation, in the management of chronic paronychia.

Conditions

  • Chronic Paronychia

Interventions

DRUG

Intralesional triamcinolone acetonide and fluconazole

Triamcinolone acetonide and fluconazole in the ratio of 1:7, yielding a triamcinolone acetonide concentration of 5mg/ml, is injected through the affected nail fold with a 30-gauge, 1-mL insulin syringe needle.

DRUG

Topical mometasone furoate and miconazole nitrate, Elica-M®

Topical treatment in the form of twice daily application of combined steroid and antifungal (mometasone furoate and miconazole nitrate, Elica-M®) till the end of treatment response or for a maximum of 3 months.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Yousra A Azzazi, Lecturer of Dermatology · Cairo University

  • Mohamed M El-Komy, Professor of Dermatology · Cairo University

  • Habiba K Edrees, Dermatology Resident · Cairo University

  • Khadija A Affify, Dermatology resident · Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-17
Primary Completion
2025-12-04
Completion
2026-05-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07311759 on ClinicalTrials.gov