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To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage

NCT07307248 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 408

Last updated 2026-01-28

No results posted yet for this study

Summary

In adults with walled-off pancreatic necrosis (WON) undergoing endoscopic ultrasound (EUS)-guided transluminal necrosectomy, does early removal of the lumen-apposing metal stent (LAMS) (at 2 weeks or immediately after the last necrosectomy) with placement of a double-pigtail plastic stent (DPT), compared to delayed LAMS removal at 4 weeks without a DPT, result in a lower rate of pancreatic fluid collection (PFC) recurrence or need for reintervention over 12 months.

Conditions

  • Walled Off Necrosis

Interventions

PROCEDURE

Standard LAMS Removal with Double-Pigtail Plastic Stent

In the early stent removal arm, LAMS will be removed at 2 weeks followed by placement of a double-pigtail plastic stent (DPT).

PROCEDURE

Standard LAMS Removal without DPT

In the standard arm, LAMS will be removed at 4 weeks.

Sponsors & Collaborators

  • Asian Institute of Gastroenterology, India

    lead OTHER

Principal Investigators

  • Deepak L Jha, (Medical Gastroenterology) · Asian Institute of Gastroenterology, Hyderabad

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-25
Primary Completion
2027-12-31
Completion
2028-12-31

Countries

  • India

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07307248 on ClinicalTrials.gov