Nelmastobart in Combination With Docetaxel in Non Small Cell Lung Cancer
NCT07306624 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 62
Last updated 2026-01-15
Summary
A Multicenter, Phase 2 Clinical Trial Based on an Adaptive Design to Evaluate the Safety and Efficacy of Nelmastobart in Combination with Docetaxel in Patients with Advanced/Metastatic Non-Small Cell Lung Cancer Who Are Resistant or Intolerant to Platinum-based Chemotherapy and/or Immunotherapy
Conditions
- Non Small Cell Lung Cancer
Interventions
- DRUG
-
Nelmastobart and Docetaxel
Nelmastobart 800mg and Docetaxel 75mg/m2
Sponsors & Collaborators
-
STCube, Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-01-10
- Primary Completion
- 2027-08-31
- Completion
- 2027-08-31
Countries
- South Korea
Study Locations
More Related Trials
-
This is a Two-cohort, Exploratory Clinical Study Assessing the Activity of Benmelstobart Combined With Chemotherapy With or Without Anlotinib in Resectable Limited-Stage Small Cell Lung Cancer
NCT06978153 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Assess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment.
NCT01750281 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Trial of AK104 in Advanced Non-Small Cell Lung Cancer
NCT05215067 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Neoadjuvant Toripalimab Plus Platinum-based Doublet for Stage III Non-small Cell Lung Cancer
NCT04304248 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)
NCT04623775 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Bortezomib With or Without Docetaxel in Treating Patients With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer
NCT00064012 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Clinical Trial of Docetaxel, Oxaliplatin Combination Chemotherapy in Patients With Stage IIIB/IV Non-adenocarcinoma, Non-small Cell Lung Cancer (NSCLC) as Second-line Treatment
NCT01497041 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Nab-paclitaxel in Sensitive and Refractory Relapsed SCLC
NCT03219762 ·Status: UNKNOWN ·Phase: PHASE2
-
Weekly Versus 3-Weekly Docetaxel Plus Cisplatin for Advanced NSCLC
NCT00319514 ·Status: COMPLETED ·Phase: PHASE2
-
Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Participants With Non-small Cell Lung Cancer (NSCLC)
NCT03739710 ·Status: COMPLETED ·Phase: PHASE2
-
Vistusertib (AZD2014) Monotherapy in Relapsed Small Cell Lung Cancer Patients Harboring RICTOR Amplification
NCT03106155 ·Status: TERMINATED ·Phase: PHASE2
-
Safety and Effect of Pertuzumab in Patients With Advanced Non-Small Cell Lung Cancer, Which Has Progressed After Prior Chemotherapy
NCT00063154 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel in Non Small Cell Lung Cancer (NSCLC)
NCT00258739 ·Status: COMPLETED ·Phase: PHASE2
-
Investigation of Safety and Efficacy of SB Injection in Patients With Advanced and Metastatic Non-small Cell Lung Cancer
NCT01305967 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)
NCT06472076 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
This is a Two-cohort, Exploratory Clinical Study Assessing the Activity of Benmelstobart Alone or Combined with Anlotinib Administered Prior to Surgery in Terms of Pathological Complete Response
NCT06851169 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Survival Study of Docetaxel and Carboplatin as Neo-Adjuvant Vs Adjuvant Chemotherapy in Early Stage NSLC
NCT00321334 ·Status: COMPLETED ·Phase: PHASE3
-
Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Metastatic Non-squamous NSCLC
NCT01673867 ·Status: COMPLETED ·Phase: PHASE3
-
Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer
NCT00003281 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel or Pemetrexed With or Without Cetuximab in Patients With Recurrent or Progressive Non-Small Cell Lung Cancer
NCT00095199 ·Status: COMPLETED ·Phase: PHASE3
-
Trial of NanoPac Intratumoral Injection in Lung Cancer
NCT04314895 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Talabostat and Docetaxel in Advanced Non-Small Cell Lung Cancer
NCT00080080 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Tobemstomig Plus Platinum-Based Chemotherapy vs Pembrolizumab Plus Platinum-Based Chemotherapy in Participants With Previously Untreated Non-Small Cell Lung Cancer
NCT05775289 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Single Agent Chemotherapy +/- Nivolumab in Patients With Advanced Squamous or Non-squamous NSCLC With Primary Resistance to Prior PD-1 or PDL-1 Inhibitor
NCT03041181 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Talabostat + Docetaxel Versus Docetaxel in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based Chemotherapy
NCT00243204 ·Status: TERMINATED ·Phase: PHASE3