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The Effect of Cryotherapy on Treatment Outcomes for Pulpotomy

NCT07303010 · Status: NOT_YET_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2025-12-24

No results posted yet for this study

Summary

The goal of this clinical trial is to investigate the effect of cryotherapy on treatment outcome for pulpotomny in permanent mature carious posterior teeth. The main question is: Do cryotherapy improve treatment outcome in interested samples?

\[primary hypothesis or outcome measure 1\] Treatment outcome by clinical and radiographic examination.

Treatment outcome from different groups will be compared at designated time points.

Conditions

  • Carious Teeth

Interventions

OTHER

Addition of Cryotherapy on pulpotomy

Experimental: Addition of Cryotherapy on pulpotomy After hemostasis is achieved, the pulpotomy area is irrigated for 5 minutes with normal saline solution, which is kept in the refrigerator set to 2.5°C (measuring with thermometer and record) by using a disposable insulated 5 ml syringe and 21-gauge needle is placed 1-2 mm above the root canal orifices and is constantly moved in a circular motion: 5 ml in each of 4 syringes, administered every 1.25 minutes per syringe.

Sponsors & Collaborators

  • Sirawut Hiran-us

    lead OTHER

Principal Investigators

  • Sirawut Hiran-us, DDS, MSc, High Grad Dip, FRCDS · Faculty of Dentistry, Chulalongkorn University

  • Sawat Pojlerdarun, DDS, Higher Grad Dip, FRCDS · Yala Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-12-30
Primary Completion
2035-12-30
Completion
2035-12-30

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07303010 on ClinicalTrials.gov