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Platelet Serotonin Deficiencies: the Strasbourg Experience

NCT07302087 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2025-12-24

No results posted yet for this study

Summary

Hemorrhagic syndromes are investigated using algorithms established by reference centers and hemostasis societies.

The investigation of platelet dense granules (nucleotide and serotonin testing) is part of the second-line tests.

It can be performed in cases of platelet aggregation abnormalities in platelet-rich plasma (PRP) suggesting a secretion abnormality, or in cases where the latter is normal, it can be performed if the patient's clinical presentation points to a primary hemostasis abnormality and the clinician wishes to pursue further investigations Intraplatelet serotonin deficiencies are often iatrogenic and may be accompanied by bleeding.

Their impact on platelet function is poorly documented.

Conditions

  • Hemorrhagic Syndrome

Sponsors & Collaborators

  • University Hospital, Strasbourg, France

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-25
Primary Completion
2026-02-28
Completion
2026-02-28

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07302087 on ClinicalTrials.gov