A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants
NCT07290283 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 176
Last updated 2026-04-27
Summary
The purpose of this study is to assess the safety and tolerability of AZD3974 and characterize the pharmacokinetics (PK) of AZD3974 following oral administration to healthy participants, including participants of Japanese and Chinese descent.
Conditions
- Healthy Participants
Interventions
- DRUG
-
AZD3974
AZD3974 will be administered as an oral solution.
- OTHER
-
Placebo
Placebo will be administered as an oral solution.
Sponsors & Collaborators
-
Parexel
collaborator INDUSTRY - lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-12-10
- Primary Completion
- 2026-10-21
- Completion
- 2026-10-21
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of AZD1613 in Healthy Participants.
NCT06995820 ·Status: RECRUITING ·Phase: PHASE1
-
This is a Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of AZD9742 After Single IV Doses in Healthy Subjects
NCT01030224 ·Status: COMPLETED ·Phase: PHASE1
-
A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants
NCT06138795 ·Status: COMPLETED ·Phase: PHASE1
-
Single and Multiple Ascending Doses of AZD1981 in Japan
NCT00698282 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers
NCT06951880 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants
NCT06122714 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446
NCT00902993 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD2423 in Healthy Volunteers
NCT00940212 ·Status: COMPLETED ·Phase: PHASE1
-
AZD9742 Single and Multiple Ascending Dose Study in Healthy Male and Female Japanese Subjects
NCT01114152 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Safety and Pharmacokinetics of AZD6793 in Healthy Japanese and Chinese Participants
NCT06368440 ·Status: COMPLETED ·Phase: PHASE1
-
AZD8529 Single Ascending Dose Study
NCT00755378 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults
NCT06469151 ·Status: COMPLETED ·Phase: PHASE1
-
Assess the Safety, Tolerability and Pharmacokinetics of AZD5213 After Single and Multiple Ascending Oral Doses in Healthy Young and Elderly Japanese Subjects
NCT01335451 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD2516 to Healthy Volunteers
NCT00754715 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate Safety, Tolerability and Pharmacokinetics (PK) (Including Food Effect) of Oral Doses of AZD5847 in Healthy Volunteers
NCT01037725 ·Status: COMPLETED ·Phase: PHASE1
-
AZD7268 Single Ascending Dose Study in Healthy Japanese Subjects
NCT00912353 ·Status: COMPLETED ·Phase: PHASE1
-
To Assess the Safety, Tolerability and Pharmacokinetics of AZD2820 After Single Ascending Doses
NCT01332214 ·Status: COMPLETED ·Phase: PHASE1
-
AZD7325 Single Ascending Dose Study in Healthy Male Japanese Subjects
NCT00769899 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability & PK of AZD0328 in Caucasian & Japanese
NCT00738959 ·Status: COMPLETED ·Phase: PHASE1
-
Investigating Safety, Tolerability and Pharmakinetics When Giving Single and Fractionated Doses of AZD3241 to Healthy Volunteers
NCT00729443 ·Status: COMPLETED ·Phase: PHASE1
-
Single + Multiple Ascending Dose and Food Effect Study of AZD7986 in Healthy Volunteers, PK, PD and Safety Study
NCT02303574 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Activity of AZD5069 When Given as a Single Dose to Healthy Male and/or Female Subjects
NCT00953888 ·Status: COMPLETED ·Phase: PHASE1
-
A Placebo-controlled Safety and Tolerability Study of Intravenous (IV) and Subcutaneous (SC) AZD1163 in Healthy Volunteers
NCT06103877 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Multiple Ascending Dose Study for AZD 7268 in Healthy Volunteers
NCT00861718 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled AZD4604 in Healthy Japanese and Chinese Participants.
NCT06519968 ·Status: COMPLETED ·Phase: PHASE1