Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma

NCT07282587 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-02-27

No results posted yet for this study

Summary

This is a two-stage Phase 2 trial evaluating the efficacy and safety of ONC206 in participants with Pheochromocytoma and Paraganglioma (PCPG).

Conditions

  • Advanced Pheochromocytoma and Paraganglioma
  • PCPG

Interventions

DRUG

ONC206

150 mg BID TIW

DRUG

ONC206: Dose 1

DRUG

ONC206: Dose 2

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-02
Primary Completion
2028-12-15
Completion
2028-12-15
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07282587 on ClinicalTrials.gov