Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma
NCT07282587 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2026-02-27
Summary
This is a two-stage Phase 2 trial evaluating the efficacy and safety of ONC206 in participants with Pheochromocytoma and Paraganglioma (PCPG).
Conditions
- Advanced Pheochromocytoma and Paraganglioma
- PCPG
Interventions
- DRUG
-
ONC206
150 mg BID TIW
- DRUG
-
ONC206: Dose 1
- DRUG
-
ONC206: Dose 2
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-01-02
- Primary Completion
- 2028-12-15
- Completion
- 2028-12-15
- FDA Drug
- Yes
Countries
- United States
Study Locations
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