STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis)
NCT07278310 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1025
Last updated 2026-04-09
Summary
To evaluate the safety and efficacy of Siegel™ TAVR System in the treatment of subjects with symptomatic severe native aortic stenosis.
Conditions
- Symptomatic Severe Native Aortic Stenosis
- Aortic Stenosis
Interventions
- DEVICE
-
TAVR Device
Commercially available TAVR Device
- DEVICE
-
Siegel TAVR Device
Siegel TAVR Device
Sponsors & Collaborators
-
MiRus
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-30
- Primary Completion
- 2028-04-30
- Completion
- 2028-04-30
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
The Safety and Effectiveness of Transcatheter Aortic Valve Raplacemet in Intermediate Risk Patients With Bicuspid Aortic Stenosis
NCT03163329 ·Status: UNKNOWN ·Phase: PHASE2
-
accuRate Evaluation of Benefit With Optimal Medical Treatment With or Without Transcatheter Valve Repair of PARADOXical Low Flow Low Gradient Aortic Stenosis
NCT03863132 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Outcomes of Transcatheter Aortic Valve Implantation in Management of Severe Symptomatic Aortic Stenosis
NCT03633383 ·Status: UNKNOWN
-
Structured Shared Decision Making for Patients Undergoing SAVR or TAVR
NCT05711186 ·Status: RECRUITING ·Phase: NA
-
Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients
NCT02701283 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
The Bicuspid Aortic Stenosis Following Transcatheter Aortic Valve Replacement Registry
NCT02394184 ·Status: COMPLETED
-
Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement
NCT04870424 ·Status: COMPLETED ·Phase: PHASE3
-
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
NCT06777368 ·Status: RECRUITING
-
The Asian Transcatheter Aortic Valve Replacement Registry
NCT02308150 ·Status: COMPLETED
-
To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Stenosis
NCT04893603 ·Status: RECRUITING ·Phase: NA
-
Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement
NCT01531374 ·Status: COMPLETED ·Phase: NA
-
Prizvalve Pro™ Transcatheter Aortic Valve Replacement Study
NCT05864456 ·Status: RECRUITING ·Phase: NA
-
Comparison of TAVR With SAVR in Younger Low Surgical Risk Patients With Severe Aortic Stenosis
NCT02825134 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Evaluate the Transcatheter Artificial Aortic Valve and Transcatheter Artificial Heart Values Delivery System
NCT03788590 ·Status: UNKNOWN ·Phase: NA
-
Portico TAVI Implant With Transfemoral Delivery System
NCT01493284 ·Status: COMPLETED ·Phase: NA
-
Targeted Testing for ATTR Among Aortic Stenosis Patients-Pilot
NCT04363294 ·Status: WITHDRAWN ·Phase: NA
-
5 Year Observation of Patients With PORTICO Valves
NCT01802788 ·Status: COMPLETED
-
Coronary Artery Disease Assessment Strategies in TAVI Patients
NCT06559332 ·Status: RECRUITING ·Phase: NA
-
Assessment of the St Jude Medical Portico Resheathable Aortic Valve System-Alternative Access
NCT03056573 ·Status: COMPLETED ·Phase: NA
-
A Prospective, Multicenter, Observational Study of the Safety and Efficacy of Emergency Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis
NCT07108478 ·Status: NOT_YET_RECRUITING
-
PrizValve® Transcatheter Aortic Valve Replacement Study
NCT04836897 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Mi-thos® Transcatheter Mitral Valve Replacement(First-in-Man Study)
NCT05784337 ·Status: COMPLETED ·Phase: NA
-
CoreValve® System Australia/New Zealand Clinical Study
NCT01015612 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy Study of MicroPort's Transcatheter Aortic Valve and Delivery System for TAVI
NCT02221921 ·Status: UNKNOWN ·Phase: NA
-
TAVIS Registry - Trilogy Heart Valve System for Management of Patients With Aortic Valve Disease
NCT05536310 ·Status: NOT_YET_RECRUITING