Identifying the Best Follow up Approach for People Who Have Had Treatment to Cure Newly Diagnosed Prostate Cancer

Summary

Over 20,000 patients a year in the UK get surgery or radiotherapy to cure their prostate cancer. These men then undergo regular check-ups to manage potential side effects and see if cancer recurs so it can be treated quickly. The organisation of these check-ups varies across the country as it is not known which approach is best. The four different established approaches are (i) check-ups performed in hospital outpatients by the same team that provided treatment; (ii) patients seen regularly by their GP with hospital referral as necessary; (iii) planned shared care between general practice and hospital follow up; or (iv) patients supported to provide checks on themselves (self-care) and reaching out to a doctor or a nurse when required. This study will compare these options to establish which is best for patients and makes the best use of the NHS resources.

Conditions

• Prostate Cancer

Interventions

OTHER

Hospital based follow up

Exclusively hospital led follow up, face-to-face or remotely by the specialist treating team.

OTHER

Primary care based follow up

After the initial hospital follow up, patients are discharged and exclusively managed by (non-specialist) general practices (GP or nurse led) in face-to-face or remote appointments, with hospital referral as necessary.

OTHER

Planned shared care follow up

An ongoing combination of general practice and hospital management

OTHER

Self-management

After initial hospital follow up, patients are discharged and managed remotely, with no scheduled review. A tracking system monitors prostate-specific antigen (PSA) tests performed in primary care or secondary care. Patients access support workers for remote consultation to discuss symptoms and request further specialist management as required.

Sponsors & Collaborators

• London School of Hygiene and Tropical Medicine

  collaborator OTHER

• University of Aberdeen

  collaborator OTHER

• University of Leeds

  collaborator OTHER

• Cardiff University

  collaborator OTHER

• University of Sheffield

  collaborator OTHER

• University of Southampton

  collaborator OTHER

• University College, London

  collaborator OTHER

• Royal Marsden NHS Foundation Trust

  collaborator OTHER

• North Bristol NHS Trust

  collaborator OTHER

• Cardiff and Vale University Health Board

  collaborator OTHER_GOV

• Liverpool University Hospitals NHS Foundation Trust

  collaborator OTHER_GOV

• National Institute for Health Research, United Kingdom

  collaborator OTHER_GOV

• Imperial College London

  lead OTHER

Principal Investigators

• Rakesh Heer, BMed Sci MB BS MRCS PhD FRCS · Imperial College London

Eligibility

Min Age

18 Years

Sex

MALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-10-31

Primary Completion

2027-07-31

Completion

2027-07-31

Countries

• United Kingdom

Study Locations