MedTrace Logo

Mouthwash Temperature and Oral Mucositis in Head and Neck Radiotherapy

NCT07252557 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2025-11-26

No results posted yet for this study

Summary

This single-center randomized controlled trial evaluates the effects of cold (15-20°C) versus room-temperature (30-35°C) water gargling on oral mucositis severity, pain, and comfort in patients with head and neck cancer undergoing radiotherapy. Participants will rinse their mouth four times daily for 30-60 seconds over a 6-week radiotherapy course, with follow-up for two additional weeks. The study hypothesizes that cold-water rinsing can reduce the severity of radiation-induced oral mucositis (RTOM) and pain, improve oral comfort, and minimize treatment interruptions.

Conditions

  • Head and Neck Cancer (H&Amp;Amp;N)
  • Radiation-induced Oral Mucositis
  • Supportive Care
  • Nursing Interventions
  • Radiotherapy Side Effects

Interventions

BEHAVIORAL

Water Rinse at Different Temperatures

rinse their mouth with cold water at approximately 15-20°C

Sponsors & Collaborators

  • Chung Shan Medical University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-01
Primary Completion
2026-12-31
Completion
2027-03-31

Countries

  • Taiwan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07252557 on ClinicalTrials.gov