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Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass

NCT07248202 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-03-17

No results posted yet for this study

Summary

This study compares ketamine/fentanyl versus ketamine/lidocaine in term of their impact on cerebral perfusion during CABG. No prior data address these effects, and the goal is to identify the induction regimen that better preserves cerebral oxygenation.

Conditions

  • Coronary Artery Disease (CAD)
  • Left Ventricular (LV) Systolic Dysfunction
  • Induction Anesthesia
  • Coronary Bypass Graft Surgery
  • Ketamine
  • Fentanyl
  • Lidocaine

Interventions

DRUG

Fentanyl (IV)

patients will receive 1 mcg/kg of Fentanyl (10 mcg/mL).

DRUG

lidocaine

patients will receive 1 mg/kg lidocaine (10mg/mL)

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2026-06-30
Completion
2026-07-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07248202 on ClinicalTrials.gov