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Composition of the Intestinal Microbiome in Patients With Recurrent Spontaneous Abortions.

NCT07246486 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2025-11-24

No results posted yet for this study

Summary

Up to 50% of all women suffer of a spontaneous abortion. Having two/three or more spontaneous abortions is one of the main reasons of unwanted childlessness. It is well known that the intestinal microbiome has many important roles in a healthy organism. Simultaneously, a dysbiosis can lead to diseases like, for example, chronic inflammatory bowel diseases, autoimmune diseases or diabetes. Several studies showed that there is a connection between a vaginal dysbiosis and premature birth or late abortion. It is still unclear what effects the composition of the intestinal microbiome before pregnancy has on the course of pregnancy.

This study will be investigate if there is a connection between the composition of the intestinal microbiome and the occurence of recurrent spontaneous abortions.

Conditions

  • Spontaneous Abortion

Sponsors & Collaborators

  • German Center for Infection Research

    collaborator OTHER

  • Dr. Natascha Köstlin-Gille

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-01
Primary Completion
2023-02-28
Completion
2023-02-28

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07246486 on ClinicalTrials.gov