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Supplementation With Sirtuin Activators in Women With Increased Body Weight

NCT07245979 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-05-22

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are:

Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing?

Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status.

Participants will:

Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.

Conditions

  • Obesity & Overweight

Interventions

DIETARY_SUPPLEMENT

Sirtuin activators

Sirtuin acitivators supplementation for 6 months

DIETARY_SUPPLEMENT

Placebo

Placebo supplementation for 6 months

Sponsors & Collaborators

  • Poznan University of Medical Sciences

    collaborator OTHER

  • NutroPharma

    collaborator INDUSTRY

  • Poznan University of Life Sciences

    lead OTHER

Principal Investigators

  • Agata Chmurzynska, Professor · Poznan Univeristy of Life Sciences

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-08
Primary Completion
2026-11-30
Completion
2027-03-01

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07245979 on ClinicalTrials.gov