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REDO-AF: Randomized Evaluation of Dual Options for AF Re-intervention

NCT07245147 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2025-11-24

No results posted yet for this study

Summary

The goal of this randomized open-label clinical trial is to evaluate two different strategies for the treatment of recurrent atrial fibrillation (AF) after AF ablation. Patients who have symptomatic, drug-refractory recurrence of AF will be randomized to either a redo AF ablation vs conduction system pacing with AV node ablation. Patients will need to have undergone at least 1 prior AF ablation to be considered eligible for the study. The current trial is a vanguard study of 16 patients and will determine the feasibility of enrolment, compare changes in quality of life, and inform the design of the definitive REDO AF trial.

Conditions

  • Atrial Fibrillation (AF)
  • AV Node Ablation
  • Left Bundle Branch Pacing

Interventions

PROCEDURE

Redo AF Ablation

Redo AF Ablation as per operator discretion

PROCEDURE

Pace and Ablate

Left bundle branch pacing with AV node ablation

Sponsors & Collaborators

  • Jacqueline Joza

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-11-30
Primary Completion
2026-12-31
Completion
2027-09-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07245147 on ClinicalTrials.gov