Insulin Resistance Among Hepatitis C Infected Children
NCT07238530 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2025-11-20
Summary
The goal of this observational study was to study the occurrence of insulin resistance in hepatitis C virus infected children who were either thalassemic or survivors of childhood malignancy and its correlation to the HCV viral load and other metabolic factors.
The main question it aims to answer is:
1. Do children infected with Hepatitis C have a higher incidence of Insulin resistance compared to healthy controls of same age and gender?
2. Is Insulin resistance occurence affected by HCV viral load, blood transfusion frequency, or metabolic factors? Researchers will compare hepatitis c infected children who are either thalassemic or survivors of childhood malignant to healthy age and sex matched controls.
Participants will be subjected to:
* standardized Questionnaires,
* physical examination and
* laboratory investigations including liver functions (ALT, AST, Alkaline phosphatase), Prothrombin time, serum ferritin level, albumin, fasting glucose, fasting insulin level and Insulin resistance assessment by HOMA IR calculation.
Conditions
- This Study is to Assess Occurence of Insulin Resistance Among Hepatits C Infected Children Whether Thalassemic or Survivors of Childhood Malignancy
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Eligibility
- Min Age
- 3 Years
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-09-30
- Primary Completion
- 2016-05-31
- Completion
- 2016-07-01
Countries
- Egypt
Study Locations
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