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Rectus-Intercostal Fascial Plane Block for Liver Transplantation Donors

NCT07233096 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2026-01-08

No results posted yet for this study

Summary

Postoperative pain control plays a crucial role in enhancing recovery and improving early mobilization in living liver donors. The rectus-intercostal fascial plane (RIFP) block is a novel ultrasound-guided regional anesthesia technique that provides anterior abdominal wall analgesia by targeting the intercostal nerves between the rectus abdominis and intercostal muscle fascia.

This prospective, randomized controlled clinical study aims to evaluate the postoperative analgesic efficacy and opioid-sparing effects of the RIFP block compared with standard intravenous analgesia in living liver donors undergoing donor hepatectomy.

Participants will be randomly assigned to two groups:

Group 1 (RIFP Block): Patients receiving an ultrasound-guided rectus-intercostal fascial plane block using 20 mL of 0.25% bupivacaine at the end of surgery, in addition to standard IV PCA (morphine).

Group 2 (Control): Patients receiving only standard IV PCA (morphine) without regional block.

Conditions

  • Liver Transplantation
  • Living Donor
  • Postoperative Pain

Interventions

OTHER

Rectus Intercostal Plane Block

Rectus intercostal plane block will be administered bilaterally at the end of the surgery and after skin closure under ultrasound guidance

OTHER

Control (No Block)

Ultrasound probe placement on the same region without needle insertion or local anesthetic injection to maintain blinding.

Sponsors & Collaborators

  • Istinye University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-22
Primary Completion
2026-05-31
Completion
2026-06-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07233096 on ClinicalTrials.gov