A Study to Assess the Relative Bioavailability of Different Subcutaneous Formulations ofAZD6234
NCT07220954 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 21
Last updated 2026-05-18
Summary
This study in healthy volunteers aims to compare blood levels and side effects after administration of different formulations of AZD6234.
This study will take place at one site in Nottingham, United Kingdom, and will enrol 21 healthy men and women aged 18-55 years.
Conditions
- Healthy Participants
Interventions
- DRUG
-
AZD6234 Formulation 1
AZD6234 Formulation 1 will be administered as a single SC injection
- DRUG
-
AZD6234 Formulation 2 (low concentration)
AZD6234 Formulation 2 (low concentration) will be administered as a single SC injection
- DRUG
-
AZD6234 Formulation 2 (high concentration)
AZD6234 Formulation 2 (high concentration) will be administered as a single SC injection
- DRUG
-
AZD6234 Formulation 3
AZD6234 Formulation 3 will be administered as a single SC injection
Sponsors & Collaborators
-
Quotient Sciences
collaborator INDUSTRY - lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-11-11
- Primary Completion
- 2026-09-09
- Completion
- 2027-04-01
Countries
- United Kingdom
Study Locations
More Related Trials
-
A Bioavailability Study Comparing 3 Different AZD1981 Tablets
NCT01311635 ·Status: COMPLETED ·Phase: PHASE1
-
A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects
NCT05294458 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
NCT07221591 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Bioavailability and Pharmacokinetic Study of Subcutaneous and Intravenous RO6811135 in Healthy Volunteers
NCT01802853 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Amount of Drug Levels in Blood and Safety of AZD5718 Formulations in Healthy Volunteers
NCT04210388 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Bioavailability of Different Formulations of AZD5718 and the Food Effect on the Selected Formulation of AZD5718 in Healthy Volunteers
NCT03420092 ·Status: COMPLETED ·Phase: PHASE1
-
To Determine the Relative Bioavailability of Different Formulations of AZD9291 and the Effect of Food.
NCT01951599 ·Status: COMPLETED ·Phase: PHASE1
-
Bioavailability of Four Oral Prototype Extended Release Formulations With BI 11634 in Healthy Male Volunteers
NCT02214953 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Healthy Men to Test if Taking Different Formulations of BI 1358894 With or Without Food Influences the Amount of BI 1358894 in the Blood
NCT03892616 ·Status: COMPLETED ·Phase: PHASE1
-
Relative Bioavailability Study in Healthy Male Subjects for ZD4054 (Zibotentan) Immediate Release Tablets.
NCT00713791 ·Status: COMPLETED ·Phase: PHASE1
-
To Evaluate the Safety and Pharmacokinetic Characteristics of AJU-C714 and C714R in Healthy Adults
NCT06933459 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Evaluate Relative Bioavailability and Food-Effect of HA121-28 Tablet B in Healthy Subjects
NCT05072535 ·Status: COMPLETED ·Phase: PHASE1
-
A Bioavailability Study Comparing Modified-release Capsules and Immediate Release Capsules in Fed and Fasting Conditions
NCT01092299 ·Status: COMPLETED ·Phase: PHASE1
-
AZD1981 Bioavailability Study of Intravenous (IV) and Oral Formulations
NCT00918398 ·Status: COMPLETED ·Phase: PHASE1
-
Compare Bioavailability of RO7239361 After Subcutaneous Injection
NCT03100630 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects
NCT01365000 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Low-Fat Food on Pexidartinib Pharmacokinetics in Healthy Volunteers
NCT03901313 ·Status: COMPLETED ·Phase: PHASE1
-
Bioavailability Study of K0706 in Healthy Subjects
NCT03316820 ·Status: COMPLETED ·Phase: PHASE1
-
To Evaluate the Safety and PK Characteristics in Healthy Volunteers
NCT06355349 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body
NCT07071974 ·Status: COMPLETED ·Phase: PHASE1
-
A Crossover Study to Evaluate Pegilodecakin (LY3500518) in Healthy Participants
NCT04194892 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY3023414 Formulations and the Effect of Food
NCT02818335 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Pharmacokinetic Interaction and Safety Between BR1018-1 and BR1018-2 in Healthy Adult Subjects
NCT05460364 ·Status: COMPLETED ·Phase: PHASE1
-
Bioequivalence Study of Azacitidine for Injection in Myelodysplastic Syndrome (MDS) Patients
NCT01152346 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess Safety, Tolerability, and Pharmacokinetics of CC-92480 Formulations in Healthy Adult Participants
NCT04839809 ·Status: COMPLETED ·Phase: PHASE1