A Study of Guselkumab in Participants With Psoriatic Arthritis (PsA) in a Real-World Setting
NCT07220824 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2026-05-08
Summary
The purpose of this study is to assess how well guselkumab works in improving symptoms of psoriatic arthritis (an inflammatory disease that affects the joints in participants with psoriasis, a skin condition that causes red, scaly patches) using muscoloskeletal ultrasound (MSUS) in a real-world setting.
Conditions
- Arthritis, Psoriatic
Sponsors & Collaborators
-
Janssen Research & Development, LLC
lead INDUSTRY
Principal Investigators
-
Janssen Research & Development, LLC Clinical Trial · Janssen Research & Development, LLC
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-04
- Primary Completion
- 2027-07-31
- Completion
- 2027-09-30
Countries
- Italy
Study Locations
More Related Trials
-
A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis With and Without Prior Exposure to Anti-TNF Agents
NCT01077362 ·Status: COMPLETED ·Phase: PHASE3
-
Potential Role of Guselkumab in Modulating PAIN Perception and Related Gene Pathways: a Proof-of-concept Study.
NCT06974474 ·Status: RECRUITING ·Phase: PHASE4
-
A Study of Guselkumab for the Treatment of Palmoplantar-non-Pustular Psoriasis
NCT03998683 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Guselkumab on Cardiovascular Risk Surrogate Markers in Participants With Moderate to Severe Plaque Psoriasis
NCT05125679 ·Status: TERMINATED ·Phase: PHASE4
-
Study of Guselkumab in Skin of Color Participants With Moderate-to-severe Plaque and/or Scalp Psoriasis
NCT05272150 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Guselkumab Versus Placebo for the Treatment of Low Body Surface Area Moderate Plaque Psoriasis
NCT06039189 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis
NCT02905331 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Secukinumab Versus Guselkumab in Clearing Psoriatic Plaques Refractory to Ustekinumab
NCT03553823 ·Status: COMPLETED ·Phase: PHASE2
-
Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy
NCT06586281 ·Status: RECRUITING ·Phase: NA
-
Multi-Center PAMPA Study
NCT05004727 ·Status: RECRUITING ·Phase: PHASE4
-
Efficacy and Safety of BMS-986165 Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA)
NCT03881059 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Characterize Profile of Participant With Psoriatic Arthritis Depending on Whether Their Disease is Managed by a Dermatologist or by a Rheumatologist, and Starting Ustekinumab
NCT03336281 ·Status: COMPLETED
-
A Study to Compare the Efficacy of Guselkumab to Fumaric Acid Esters for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
NCT02951533 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis
NCT06176508 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate Further Therapeutic Strategies With Guselkumab in Participants With Moderate-to-Severe Plaque-Type Psoriasis
NCT03818035 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
NCT03451851 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of Guselkumab (TREMFYA) in Chinese Participants With Moderate to Severe Plaque Psoriasis
NCT04914429 ·Status: COMPLETED ·Phase: PHASE4
-
Therapeutic Drug Monitoring of Guselkumab in Psoriasis Patients
NCT04080648 ·Status: COMPLETED ·Phase: PHASE4
-
Psoriasis Longitudinal Assessment and Registry
NCT00508547 ·Status: ACTIVE_NOT_RECRUITING
-
An Efficacy and Safety Study of Ustekinumab (CNTO 1275) in Participants With Plaque Psoriasis
NCT00723528 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Demonstrate the Efficacy, Safety and Tolerability of Intravenous Secukinumab up to 52 Weeks in Subjects With Active Psoriatic Arthritis
NCT04209205 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis
NCT01172938 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis
NCT06934226 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs
NCT04908202 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis
NCT02397382 ·Status: COMPLETED ·Phase: PHASE1