Reducing Antibiotic Use by Implementation of Stewardship in Primary and Urgent Care
NCT07217002 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 420
Last updated 2026-04-14
Summary
The goal of this project is to reduce unnecessary antibiotic use for children with ARTIs (Acute Respiratory Tract Infections) by implementing "outpatient antibiotic stewardship" across the Children's Hospital of Philadelphia (CHOP) Primary and Urgent Care Network to:
1. Reduce unnecessary antibiotic prescribing for the most common infections in children.
2. Reduce unnecessary a) broad-spectrum and b) longer-course antibiotic therapy for ear infections, Strep throat, sinus infections, and pneumonia.
Conditions
- Community Acquired Pneumonia (CAP)
- Sinusitis
- Strep Pharyngitis
- Acute Otitis Media (AOM)
Interventions
- OTHER
-
Online Educational Modules
Online educational modules for clinicians that describe optimal antibiotic use and provide strategies to communicate with families about antibiotic prescribing for ARTIs. Modules are assigned through CHOP's internal learning website and assigned to every single primary care provider.
- OTHER
-
Prescribing Feedback Reports
Prescribing feedback reports distributed quarterly that show clinicians how their prescribing and Group A Strep testing compares to their peers and to professional guideline recommendations. Will include metrics of overall prescribing and show choice and duration for antibiotics given ear infections, Strep throat, sinus infections, and pneumonia. The goal of the feedback reports is to show clinicians how often they are prescribing antibiotics, and when they do prescribe antibiotics are they doing so with right antibiotic and for the correct duration.
- OTHER
-
Clinical Decision Support
Clinical decision support built into the electronic health record to help clinicians choose the right antibiotics for the right number of days. Using information from guidelines and clinical pathways created by CHOP to help providers continue to optimize their prescribing practices.
- OTHER
-
Live, hybrid in-person and online educational sessions
Live, hybrid in-person and online educational sessions that explain the project, describe best prescribing practices and allow clinicians to talk directly with project team members. Study leaders visit all 31 practices across the network.
Sponsors & Collaborators
-
Patient-Centered Outcomes Research Institute
collaborator OTHER -
Children's Hospital of Philadelphia
lead OTHER
Principal Investigators
-
Rebecca Same, MD · Children's Hospital of Philadelphia
-
Louis Bell, MD · Children's Hospital of Philadelphia
Eligibility
- Min Age
- 6 Months
- Max Age
- 12 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-18
- Primary Completion
- 2028-05-31
- Completion
- 2029-05-31
Countries
- United States
Study Locations
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