Reducing Antibiotic Use by Implementation of Stewardship in Primary and Urgent Care

NCT07217002 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 420

Last updated 2026-04-14

No results posted yet for this study

Summary

The goal of this project is to reduce unnecessary antibiotic use for children with ARTIs (Acute Respiratory Tract Infections) by implementing "outpatient antibiotic stewardship" across the Children's Hospital of Philadelphia (CHOP) Primary and Urgent Care Network to:

1. Reduce unnecessary antibiotic prescribing for the most common infections in children.
2. Reduce unnecessary a) broad-spectrum and b) longer-course antibiotic therapy for ear infections, Strep throat, sinus infections, and pneumonia.

Conditions

  • Community Acquired Pneumonia (CAP)
  • Sinusitis
  • Strep Pharyngitis
  • Acute Otitis Media (AOM)

Interventions

OTHER

Online Educational Modules

Online educational modules for clinicians that describe optimal antibiotic use and provide strategies to communicate with families about antibiotic prescribing for ARTIs. Modules are assigned through CHOP's internal learning website and assigned to every single primary care provider.

OTHER

Prescribing Feedback Reports

Prescribing feedback reports distributed quarterly that show clinicians how their prescribing and Group A Strep testing compares to their peers and to professional guideline recommendations. Will include metrics of overall prescribing and show choice and duration for antibiotics given ear infections, Strep throat, sinus infections, and pneumonia. The goal of the feedback reports is to show clinicians how often they are prescribing antibiotics, and when they do prescribe antibiotics are they doing so with right antibiotic and for the correct duration.

OTHER

Clinical Decision Support

Clinical decision support built into the electronic health record to help clinicians choose the right antibiotics for the right number of days. Using information from guidelines and clinical pathways created by CHOP to help providers continue to optimize their prescribing practices.

OTHER

Live, hybrid in-person and online educational sessions

Live, hybrid in-person and online educational sessions that explain the project, describe best prescribing practices and allow clinicians to talk directly with project team members. Study leaders visit all 31 practices across the network.

Sponsors & Collaborators

Principal Investigators

  • Rebecca Same, MD · Children's Hospital of Philadelphia

  • Louis Bell, MD · Children's Hospital of Philadelphia

Eligibility

Min Age
6 Months
Max Age
12 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-18
Primary Completion
2028-05-31
Completion
2029-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07217002 on ClinicalTrials.gov