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Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas

NCT07215130 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2025-10-10

No results posted yet for this study

Summary

This study aims to evaluate the feasibility and tissue selectivity of a novel surgical technology, the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity, in the management of ovarian endometriomas. Ovarian endometriomas are cysts caused by endometriosis that can damage ovarian reserve when treated by conventional surgery. In this study, ovarian cyst wall specimens are examined ex vivo using different Tissue Select settings of the CUSA device. Histopathological analyses are performed to determine whether endometriotic epithelium can be selectively removed while preserving normal ovarian tissue. The findings may contribute to developing fertility-preserving surgical approaches for women with endometriomas.

Conditions

  • Ovarian Endometrioma
  • Endometriosis

Interventions

DEVICE

Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity

Ex vivo application of the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity device to ovarian endometrioma cyst wall specimens. Tissue Select settings from 0 to 4 are used to evaluate tissue selectivity, specifically removal of endometriotic epithelium while preserving normal ovarian stroma. Samples are subsequently analyzed histopathologically.

Sponsors & Collaborators

  • Kanazawa University

    lead OTHER

Principal Investigators

  • Kaoru Abiko, MD, PhD · Kanazawa University, Department of Obstetrics and Gynecology

Eligibility

Min Age
20 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-30
Primary Completion
2027-03-31
Completion
2028-03-31

Countries

  • Japan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07215130 on ClinicalTrials.gov