Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
NCT07204275 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 176
Last updated 2026-05-11
Summary
The purpose of this study is to evaluate the efficacy, safety, and tolerability of povetacicept in participants with primary membranous nephropathy (pMN).
Conditions
Interventions
- DRUG
-
Povetacicept
Solution for Subcutaneous Injection.
- DRUG
-
Capsules for Oral Administration.
Sponsors & Collaborators
-
Zai Lab (Shanghai) Co., Ltd. (for China only)
collaborator UNKNOWN -
Vertex Pharmaceuticals Incorporated
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-30
- Primary Completion
- 2028-12-29
- Completion
- 2028-12-29
- FDA Drug
- Yes
Countries
- United States
- Australia
- Brazil
- China
- Czechia
- Germany
- Hungary
- Ireland
- Italy
- Japan
- South Korea
- Spain
- United Kingdom
Study Locations
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