A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
NCT07197554 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 171
Last updated 2026-02-18
Summary
A Phase 1/1B Study of ST-01156 in Patients with Advanced Solid Malignancies
Conditions
- Advanced Solid Tumors
- Ewing Sarcoma
- Hepatocellular Carcinoma (HCC)
- Biliary Tract Cancer (BTC)
Interventions
- DRUG
-
ST-01156
ST-01156 is an orally administered degrader of RBM39, a protein frequently upregulated in cancer
Sponsors & Collaborators
-
SEED Therapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 16 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-01
- Primary Completion
- 2029-12-31
- Completion
- 2029-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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