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Treatment of Tinnitus With Olanzapine

NCT07190482 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-09-24

No results posted yet for this study

Summary

This research aims to evaluate the effects of the drug olanzapine on the discomfort caused by tinnitus according to each patient's personality traits. Olanzapine is a drug used as an antipsychotic whose mechanism of action makes it potentially useful for the treatment of tinnitus.

Conditions

  • Tinnitus
  • Tinnitus, Subjective

Interventions

DRUG

Olanzapine 5 Mg ORAL TABLET

OLANZAPINE ARM

DRUG

Placebo Drug

placebo administered for 8 weeks

Sponsors & Collaborators

  • University of Sao Paulo

    lead OTHER

Principal Investigators

  • Research Ethics Committee (CEP) Research Ethics Committee (CEP) · Research Ethics Committee (CEP)

  • JEANNE OITICICA, MD PhD · Research Ethics Committee (CEP)

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2024-12-20
Completion
2025-01-20

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07190482 on ClinicalTrials.gov