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SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity

NCT07188688 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 57

Last updated 2025-09-23

No results posted yet for this study

Summary

1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis.
2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels.
3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.

Conditions

  • Shear Wave Elastography

Interventions

DEVICE

Musculoskeletal Ultrasound Device

Musculoskeletal Ultrasound assessment by LOGIQ P10 from General Electric (GE) Healthcare, each patient will be evaluated by grey scale, power doppler MSUS and Shear Wave Elastography (SWE)

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Eman Abbas M Alkady, Professor · Rheumatology, Rehabilitation and Physical Medicine, Assiut University Hospitals

  • Doaa Kamal M. Abdelhafez, Associate Professor · Rheumatology, Rehabilitation and Physical Medicine, Assiut University Hospitals

  • Nesreen Ismail Ibrahim, Lecturer · Rheumatology, Rehabilitation and Physical Medicine, Assiut University Hospitals

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-31
Primary Completion
2026-10-31
Completion
2026-11-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07188688 on ClinicalTrials.gov