Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)
NCT07182955 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2025-09-19
Summary
The main goal is to understand what causes reduced fitness in ANOCA and whether targeted exercise can help improve it.
This study aims to better understand why patients with Angina and No Obstructive Coronary Artery Disease (ANOCA) have poor cardiorespiratory fitness and its effect on quality of life.
Investigators also want to see if a structured high-intensity exercise program (HIIT), done with remote monitoring, can safely improve heart function, fitness, and quality of life in these patients. The Investigators will use a special exercise test called cardiopulmonary exercise testing to look for patterns that can help explain exercise limitations and quality of life in ANOCA before and after a remote high-intensity exercise program.
Conditions
- MINOCA
- Shortness of Breath
- Atherosclerotic Heart Disease of Native Coronary Artery
Interventions
- BEHAVIORAL
-
EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Remote 4 weeks of high-intensity interval exercise training on three non-consecutive days of the week.
Sponsors & Collaborators
-
University of Virginia
lead OTHER
Principal Investigators
-
Jamieson M Bourque, MD, MHS · University of Virginia
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-11
- Primary Completion
- 2026-03-30
- Completion
- 2026-04-14
Countries
- United States
Study Locations
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