MB-CART2019.1 in Refractory Multiple Sclerosis
NCT07178431 · Status: RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2026-05-11
Summary
The goal of this trial is to assess the feasibility, safety and preliminary efficacy of MB-CART2019.1 in patients with active refractory primary and secondary progressive MS.
Conditions
- Multiple Sclerosis
- CAR T Cell Therapy
Interventions
- BIOLOGICAL
-
MB-CART2019.1
CAR T cell therapy
Sponsors & Collaborators
-
Miltenyi Biomedicine GmbH
lead INDUSTRY
Principal Investigators
-
Volker Siffrin PD. Dr. · Charite University, Berlin, Germany
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-01
- Primary Completion
- 2030-08-16
- Completion
- 2030-08-16
Countries
- Germany
Study Locations
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