A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)
NCT07170644 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2026-05-08
Summary
This study is being conducted to characterize the efficacy and safety of nirogacestat in Japanese adults with progressing desmoid tumors/aggressive fibromatosis.
Conditions
- Desmoid Tumor
- Aggressive Fibromatosis
Interventions
- DRUG
-
Nirogacestat oral tablet
Nirogacestat tablet
Sponsors & Collaborators
-
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-08
- Primary Completion
- 2027-03-31
- Completion
- 2029-10-31
Countries
- Japan
Study Locations
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