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Post-operative Pain After Different Irrigation and Disinfection Methods in Single-rooted Teeth

NCT07170098 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-01-12

No results posted yet for this study

Summary

This randomized clinical trial aimed to evaluate post-operative pain (PP) in single-rooted teeth with asymptomatic apical periodontitis following final irrigation with sonic activation systems (EDDY and EndoActivator), with and without adjunctive 980-nm diode laser disinfection. Eighty patients were randomized into four groups: Group 1 (EDDY), Group 2 (EndoActivator), Group 3 (EDDY + laser), and Group 4 (EndoActivator + laser). PP intensity and analgesic intake were recorded at 8, 24, 48 hours, and on day 7. The study found no significant differences in PP or analgesic use among the groups, indicating that laser-assisted or different sonic activation methods did not reduce post-operative pain.

Conditions

  • Post Operative Pain
  • Apical Periodontitis
  • Asymptomatic Infections

Interventions

DEVICE

EDDY sonic irrigation system

Sonic activation of irrigating solutions during endodontic treatment.

DEVICE

EndoActivator (EA) sonic irrigation system

Sonic activation of irrigating solutions during endodontic treatment.

DEVICE

980-nm diode laser

Diode laser irradiation during endodontic treatment.

Sponsors & Collaborators

  • Biruni University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-08-10
Primary Completion
2025-08-11
Completion
2025-10-31

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07170098 on ClinicalTrials.gov