Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension
NCT07168902 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 252
Last updated 2026-05-07
Summary
Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults with Primary Open Angle Glaucoma or Ocular Hypertension
Conditions
Interventions
- DRUG
-
BL1107 Low dose
Dosed twice daily for 28 days.
- DRUG
-
BL1107 High dose
Dosed twice daily for 28 days.
- DRUG
-
Timolol maleate 0.5%
Dosed twice daily for 28 days.
Sponsors & Collaborators
-
Bausch & Lomb Incorporated
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-24
- Primary Completion
- 2026-05-31
- Completion
- 2026-05-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension
NCT01915940 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00314158 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
NCT00332540 ·Status: COMPLETED ·Phase: PHASE3
-
MK0507A Clinical Study in Patients With Glaucoma and Ocular Hypertension (0507A-149)(COMPLETED)
NCT00449956 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy Study of Different Formulations of Bimatoprost Once-Daily in Patients With Glaucoma or Ocular Hypertension
NCT00652496 ·Status: COMPLETED ·Phase: PHASE2
-
24-hour IOP-lowering Effect of 0.01% Bimatoprost
NCT01271686 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Glaucoma or Ocular Hypertension in Patients Within the United States
NCT00800267 ·Status: COMPLETED ·Phase: PHASE3
-
Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension
NCT01749930 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension
NCT02247804 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension
NCT00822055 ·Status: COMPLETED ·Phase: PHASE4
-
Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma
NCT03131167 ·Status: COMPLETED ·Phase: PHASE1
-
Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination
NCT00941096 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension
NCT00672997 ·Status: COMPLETED ·Phase: PHASE3
-
Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension
NCT01749904 ·Status: COMPLETED ·Phase: PHASE3
-
Study Comparing the Safety and Efficacy of BOL-303259-X to Latanoprost in Subjects With Glaucoma or Ocular Hypertension
NCT01223378 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-Angle Glaucoma
NCT00753168 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients
NCT00069719 ·Status: COMPLETED ·Phase: PHASE2
-
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension
NCT01310777 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00314171 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension
NCT02061683 ·Status: COMPLETED ·Phase: PHASE4
-
Dose-Ranging Study of the Bimatoprost Ocular Insert
NCT02358369 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Travoprost/Timolol BAC-free
NCT00760539 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Brinzolamide and Timolol When Added to Travoprost in Primary Open-angle Glaucoma or Ocular Hypertension
NCT00372827 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)
NCT02339584 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and IOP-Lowering Effects of WB007
NCT04149899 ·Status: COMPLETED ·Phase: PHASE1/PHASE2