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Is There a Relationship Between Uric Acid Level and Liver Fibrosis in Obese Patients

NCT07168551 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 111

Last updated 2025-09-15

No results posted yet for this study

Summary

1. Identifying the association between hyperuricemia and NAFLD can lead to early detection and prevention of liver fibrosis in adult obese patients.
2. Understanding the relationship between hyperuricemia and NAFLD can inform targeted therapy, such as urate-lowering treatment, to potentially slow disease progression.

3 - To examine the relationship between serum uric acid levels and liver fibrosis severity\*: Assessing the correlation between serum uric acid levels and the severity of liver fibrosis in adult obese patients with NAFLD.

4- To identify potential mechanisms underlying the association\*: Exploring the potential mechanisms by which hyperuricemia may contribute to the development and progression of NAFLD and liver fibrosis in adult obese patients.

Conditions

  • Hyperuricemia
  • NAFLD (Nonalcoholic Fatty Liver Disease)
  • Liver Fibrosis

Interventions

DIAGNOSTIC_TEST

*Lab Methods:* 1- Serum Uric Acid levels 2-Liver Function Tests 3- Lipid Profile . 4- Haemoglobin A1c level . 5- Serum glucose level .

Lab methods

RADIATION

*Imaging Studies:* 1- Ultrasound 2 - FibroScan

Imaging

DEVICE

Instruments:* 1- *Automated Analyzers*: Used for blood tests, such as serum uric acid and liver function tests.

Instrument

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2026-10-01
Completion
2026-12-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07168551 on ClinicalTrials.gov