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The Effect of DNS-Based Training Combined With PFMT on LUTS and Pelvic Floor Functions in Women With MS

NCT07166809 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2026-05-06

No results posted yet for this study

Summary

The goal of this randomized controlled trial is to investigate whether adding Dynamic Neuromuscular Stabilization (DNS)-based training to Pelvic Floor Muscle Training (PFMT) can improve lower urinary tract symptoms (LUTS) and pelvic floor functions in women with multiple sclerosis (MS), aged 28-54 years.

The main questions it aims to answer are:

Does DNS combined with PFMT improve lower urinary tract symptoms more effectively than PFMT alone?

Does DNS combined with PFMT enhance pelvic floor muscle function more effectively than PFMT alone?

Researchers will compare PFMT alone versus PFMT combined with DNS-based stabilization exercises to see if DNS provides additional benefits.

Participants will:

Perform an 8-week remotely monitored Pelvic Floor Muscle Training program.

In the DNS+PFMT group, complete supervised Dynamic Neuromuscular Stabilization exercises three times a week.

Undergo assessments including:

Urinary Symptom Profile questionnaire,

International Consultation on Incontinence Questionnaire-Short Form,

Overactive Bladder Questionnaire (8-item version),

Vaginal palpation using the PERFECT (Power, Endurance, Repetitions, Fast contractions, Every Contraction Timed) scheme,

Electromyography (muscle electrical activity measurement) for pelvic floor muscles evaluation.

Conditions

  • Women With Multiple Sclerosis
  • Multiple Sclerosis
  • Lower Urinary Track Symptoms
  • Pelvic Floor Disorder

Interventions

OTHER

Pelvic Floor Muscle Training (PFMT)

A structured pelvic floor muscle training program delivered remotely for 8 weeks, including exercises designed to strengthen and improve the endurance, coordination, and control of the pelvic floor muscles.

OTHER

Pelvic Floor Muscle Training combined with Dynamic Neuromuscular Stabilization (PFMT+DNS)

Participants received the same 8-week remotely monitored pelvic floor muscle training program as the PFMT group, in addition to supervised Dynamic Neuromuscular Stabilization exercises three times per week. DNS exercises aimed to enhance core stability, postural control, and coordination to support pelvic floor muscle function.

Sponsors & Collaborators

  • The Scientific and Technological Research Council of Turkey

    collaborator OTHER

  • Ondokuz Mayıs University

    lead OTHER

Principal Investigators

  • SEDA KILIC, DR. · Ondokuz Mayıs University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2024-09-27
Completion
2025-08-27

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07166809 on ClinicalTrials.gov