Safety and Efficacy of NK510 to Treat Gastric Cancer and Colorectal Cancer
NCT07166263 · Status: NOT_YET_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2025-09-10
Summary
This study will evaluate the safety and efficacy of NK510 in the treatment of relapsed and refractory advanced gastric cancer and colorectal cancer.NK510 will be administered by intravenous infusion for systemic therapy and intraperitoneal perfusion therapy. The safety and efficacy of this treatment will be evaluated.
Conditions
- Gastric Cancer (GC)
- Colorectal Cancer
Interventions
- DRUG
-
NK510
NK510 will be administered through intravenous infusion, once a week for a total of six times.
- DRUG
-
NK510
NK510 will be administered through intraperitoneal perfusion on D1, D4, and D7 of the first week for a total of 3 times, with each 3-week cycle constituting a total of 2 cycles.
Sponsors & Collaborators
-
Base Therapeutics (Shanghai) Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-11-30
- Primary Completion
- 2027-06-30
- Completion
- 2027-12-31
Countries
- China
Study Locations
More Related Trials
-
Study of DP303c Injection in Patients With Advanced or Metastatic Gastric Cancer
NCT04826107 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of FMT Combined With Nivolumab in Gastric Cancer
NCT05001360 ·Status: WITHDRAWN ·Phase: NA
-
A Study of Genomic-guided 'Standard-of-care' Chemotherapy for in Advanced Gastric Cancer Patients
NCT01100801 ·Status: UNKNOWN ·Phase: PHASE2
-
Personalized Tumor Neoantigen mRNA Therapy for Advanced Intrahepatic Cholangiocarcinoma
NCT06956716 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Evaluate Nivolumab in Patients With Unresectable Advanced/Metastatic Gastric Cancer and Gastroesophageal Junction Cancer
NCT06452329 ·Status: COMPLETED
-
A Phase I Study of S-1 Plus Irinotecan and Oxaliplatin in Advanced Gastrointestinal Malignancy
NCT00506207 ·Status: UNKNOWN ·Phase: PHASE1
-
EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers
NCT05176665 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of KN026-based Combination Therapy in HER2-positive Gastric Cancer
NCT07332533 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Cabozantinib in High Grade Neuroendocrine Neoplasms
NCT04412629 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer
NCT02862561 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Transarterial Chemoembolization With Lipiodol in the Treatment of Initial Unresectable Gastric Cancer (GC)
NCT05361161 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Genotype-drive Study of Irinotecan-Cisplatin Combination for Advanced Gastric Cancer
NCT01444521 ·Status: COMPLETED ·Phase: PHASE2
-
Study of S1 Efficacy and Toxicity as Second-line Treatment on Inoperable or Advanced Gastric Cancers
NCT01650766 ·Status: UNKNOWN
-
A Phase II Study of Irinotecan, Oxaliplatin, Plus TS-1 in Untreated Metastatic Gastric Cancer
NCT00512681 ·Status: COMPLETED ·Phase: PHASE2
-
Tirelizumab in Combination With Chemoradiation in Patients With Unresectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
NCT05528367 ·Status: UNKNOWN ·Phase: PHASE2
-
KN026 in Patients With HER2 Expressing Gastric/Gastroesophageal Junction Cancer
NCT03925974 ·Status: COMPLETED ·Phase: PHASE2
-
To Evaluate KC1036 in the Patients with Advanced Digestive System Tumors
NCT05260385 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Single-arm, Phase II Exploratory Study of Sintilimab in Combination With Chemoradiotherapy in Elderly Patients With Locally Advanced Gastric Cancer
NCT06555471 ·Status: RECRUITING ·Phase: PHASE2
-
Study to Evaluate the Safety, Preliminary Efficacy and Pharmacokinetics of 3810
NCT03260179 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase I/II Study of Neoadjuvant Chemoradiotherapy With S-1/ Oxaliplatin in Patients With Gastric Cancer: Randomized Phase II Study of S-1/RT vs. S-1/Oxaliplatin/RT
NCT01106066 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Anlotinib Hydrochloride Combined With Nivolumab in the Treatment of Gastric and Esophageal Cancer
NCT04503967 ·Status: UNKNOWN ·Phase: PHASE2
-
Using Genetic Polymorphisms to Predict the Efficacy and Toxicity - A Gastric Adenocarcinoma Study
NCT01558011 ·Status: TERMINATED ·Phase: PHASE2
-
Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer
NCT02873520 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Taxotere New Indication - Gastric Cancer Treatment Registration Trial
NCT00811447 ·Status: COMPLETED ·Phase: PHASE3
-
Neoadjuvant Nab-Paclitaxel Plus Oxaliplatin, S-1, and Sintilimab in Early-Onset Resectable Gastric Cancer
NCT07018063 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2