Evaluation of Bone Mineral Density Indications and Outcomes in Female Adolescents: Implications for Early Detection of Osteopenia/Osteoporosis and Gynecologic Practice

NCT07164248 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2025-09-15

No results posted yet for this study

Summary

This retrospective study evaluates bone mineral density (BMD) measurements obtained by dual-energy X-ray absorptiometry (DEXA) in adolescent girls aged 12 to 21 years at a tertiary care center. The study focuses on patients referred from the adolescent gynecology clinic as well as from other medical specialties.

Key objectives are:

Comparing the BMD indications and results requested from the gynecology department with the indications and BMD results requested from other departments. Thus, the BMD scores of patients with hypogonadism can be compared with other groups at risk for bone health.

To assess BMD Z-scores across specific gynecologic diagnoses, including premature ovarian insufficiency, functional hypothalamic amenorrhea (FHA), and hypogonadotropic hypogonadism.

To analyze the relationship between gynecologic clinical features-such as age at menarche and duration of amenorrhea-and BMD Z-scores.

By combining clinical, hormonal, and densitometric data, this study aims to identify risk factors for low bone density in adolescents, support earlier recognition of osteopenia/osteoporosis, and provide guidance for appropriate interventions in adolescent gynecology practice.

Conditions

  • Bone Density
  • Osteopenia
  • Amenorrhea
  • Primary Amenorrhea

Sponsors & Collaborators

  • Bagcilar Training and Research Hospital

    lead OTHER_GOV

Principal Investigators

  • Nursen Kurtoglu · Bagcilar Training and Research Hospital

Eligibility

Min Age
12 Years
Max Age
21 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-01
Primary Completion
2025-06-15
Completion
2025-08-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07164248 on ClinicalTrials.gov