Changes in Body Composition of Patients With Obesity Related Tumors and Their Impact on Clinical Outcomes: a Multicenter Prospective Cohort Study
NCT07161167 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 6743
Last updated 2025-09-08
Summary
Over the past 20 years, China's obesity rates have surged, increasing cancer burden. Obesity links to 13 cancers via metabolic effects of visceral fat and insulin resistance, while sarcopenic obesity (BMI-independent) may worsen outcomes. Traditional BMI lacks precision; advanced methods (e.g., BIA/CT) are needed. Existing studies show inconsistent results, possibly due to heterogeneity. This multicenter prospective cohort study uses imaging to assess body composition changes (fat/muscle) in obesity-related tumors and their impact on survival, recurrence, and quality of life, and explore the underlying mechanism.
Conditions
- Obesity Rekated Cancer
- Body Composition Changes
- Survival
- Mechanism
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-09-15
- Primary Completion
- 2030-09-30
- Completion
- 2030-09-30
Countries
- China
Study Locations
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