Phase I Study of HSK42360 in Malignant Brain Tumors With BRAF V600 Mutation
NCT07158710 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 159
Last updated 2025-09-08
Summary
This is a phase I, open-label, dose-escalation and expansion study to evaluate the safety, tolerability, PK of HSK42360 when given orally in pediatric patients with active BRAF V600 mutation recurrent malignant brain tumors.
Conditions
- Malignant Brain Tumors
Interventions
- DRUG
-
HSK42360
Oral administration, QD/BID
Sponsors & Collaborators
-
Haisco Pharmaceutical Group Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-15
- Primary Completion
- 2029-05-23
- Completion
- 2029-12-03
Countries
- China
Study Locations
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