Study of SYN818 With Olaparib for the Treatment of Locally Advanced or Metastatic Solid Tumors
NCT07156253 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 110
Last updated 2025-09-05
Summary
This interventional study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of SYN818 with Olaparib in adult patients with locally advanced or metastatic solid tumors
Conditions
- Metastatic Solid Tumor
- Ovarian Cancer
- Breast Cancer
- BRCA 1 /2 and / or HRD
- Advanced Solid Tumors
Interventions
- DRUG
-
SYN818 and Olaparib will be administered
Patients will orally receive SYN818 and Olaparib
Sponsors & Collaborators
-
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-26
- Primary Completion
- 2028-08-25
- Completion
- 2029-02-25
Countries
- China
Study Locations
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