No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study
NCT07146698 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2025-09-11
Summary
this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.
Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
- Sedation and Analgesia
Interventions
- BEHAVIORAL
-
daily Interruption of Sedation
The patients will be managed by DIS. Richmond agitation and sedation score (RASS) will be used for monitoring the depth of sedation
Sponsors & Collaborators
-
Benha University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-11-01
- Primary Completion
- 2025-08-30
- Completion
- 2025-10-31
Countries
- Egypt
Study Locations
More Related Trials
-
Evaluation of an Analgosedation Protocol in Mechanically Ventilated Patients
NCT02100735 ·Status: WITHDRAWN ·Phase: NA
-
VSV Versus PSV as a Weaning Mode of Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
NCT03278795 ·Status: UNKNOWN ·Phase: NA
-
The Application of Different Sedation Protocols in ICU Patients With Severe Pneumonia
NCT06514781 ·Status: RECRUITING
-
Fiberoptic Bronchoscopy in Severe Ventilator-associated Pneumonia
NCT07149909 ·Status: COMPLETED ·Phase: NA
-
Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
NCT03230617 ·Status: UNKNOWN
-
Optimization of Ventilator Setting for Acute Exacerbations of Chronic Obstructive Pulmonary Disease
NCT01291303 ·Status: COMPLETED ·Phase: NA
-
Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation - Effects on Physical Function
NCT02034942 ·Status: COMPLETED ·Phase: NA
-
Non-interventional Comparison of Sedatives on Weaning From Mechanical Ventilation in Intensive Care Patients
NCT01707680 ·Status: TERMINATED
-
Noninvasive Ventilation Weaning Protocol in COPD
NCT07133711 ·Status: COMPLETED ·Phase: NA
-
Dexmeditomedine Versus No Sedation in Management of Agitation in COPD Patients Receiving Noninvasive Ventilation
NCT05774145 ·Status: NOT_YET_RECRUITING
-
Mechanical Power Versus Diaphragmatic Excursion As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients
NCT06510517 ·Status: NOT_YET_RECRUITING
-
Impact of Humidification on Sleep Quality During Home Non Invasive Ventilation
NCT03561974 ·Status: COMPLETED ·Phase: NA
-
Ventilator Asynchrony as a Predictor of Weaning Failure
NCT04735497 ·Status: COMPLETED
-
Evaluation of Sedation in COVID-19 ARDS
NCT04667936 ·Status: COMPLETED
-
Sleep in Critically Ill Patients on Mechanical Ventilation in ICU
NCT02434341 ·Status: COMPLETED
-
Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
NCT07308171 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Patient-Ventilator Interactions in Chronic Obstructive Pulmonary Diseases (COPD) Under Non-Invasive Ventilation
NCT01180439 ·Status: COMPLETED ·Phase: NA
-
Ventil Device Usefulness in Mechanically Ventilated ICU Patients
NCT04355754 ·Status: UNKNOWN ·Phase: NA
-
Ultrasound-Assessed Diaphragmatic Dysfunction as a Predictor of Weaning Outcome
NCT04825509 ·Status: COMPLETED
-
Pilot Study on Pairing Sedation Strategies and Weaning
NCT02219659 ·Status: COMPLETED ·Phase: NA
-
Comparative Study on the Effectiveness, Comfort and Compliance of HFNC and Noninvasive Mechanical Ventilation BiPAP Mode in the Treatment of Hypoxemia Patients
NCT05784636 ·Status: UNKNOWN ·Phase: NA
-
Advantages and Disadvantages of Long Term Sedation in Intensive Care Unit Patients
NCT00466492 ·Status: COMPLETED ·Phase: NA
-
The Study Seeks to Determine Potential Correlations Between Ventilation and Hematological Alterations, Contributing to a Better Understanding of Its Physiological Effects and Optimizing Patient Management in Critical Care Settings.
NCT07030114 ·Status: NOT_YET_RECRUITING
-
Efects of Noninvasive Mechanical Ventilation and Conventional Mechanical Ventilation in Patients With Severe Comunity Pneumonia
NCT00523497 ·Status: TERMINATED ·Phase: NA
-
Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Patients with Chronic Obstructive Bronchopneumopathy.
NCT06653933 ·Status: NOT_YET_RECRUITING