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Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study

NCT07146685 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 168

Last updated 2025-08-28

No results posted yet for this study

Summary

Randomized control study that compares different concentrations of local anesthetic to investigate whether a lower concentration of local anesthetic would contribute to lower rebound pain scores at 24 hours post op in patients undergoing anatomic or reverse total shoulder arthroplasty.

Conditions

  • Rebound Pain
  • Shoulder Arthroplasty
  • Interscalene Block

Interventions

DRUG

Bupivacaine

We are comparing two concentrations of the same drug: 10 ml of 0.5% and 20 ml of 0.25%; We will use the same milligram dose (50 mg).

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Leon N Grinman, DO · UVA

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-01
Primary Completion
2028-01-01
Completion
2029-01-01
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07146685 on ClinicalTrials.gov