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Comparison of Probiotic Effects on the Outcomes of Patients After Colorectal Cancer Surgery

NCT07144475 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2025-08-27

No results posted yet for this study

Summary

This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery. Researchers will compare probiotic to see if Lactobacillus casei Shirota improves gastrointestinal function, sepsis incidence, C-reactive protein (CRP), interleukin 6 (IL-6), and length of stay better than Lactobacillus acidophilus. Participants will take probiotics three times daily for three days before surgery.

Conditions

Interventions

BIOLOGICAL

Lactobacillus casei Shirota

Consumption of Lactobacillus casei Shirota three times daily for three days before surgery at 6 AM, 2 PM and 10 PM.

BIOLOGICAL

Lactobacillus acidophilus

Consumption of Lactobacillus acidophilus three times daily for three days before surgery at 6 AM, 2 PM and 10 PM.

Sponsors & Collaborators

  • Dharmais National Cancer Center Hospital

    lead OTHER_GOV

Principal Investigators

  • Berial D Marzaini, MD · Faculty of Medicine, University of Indonesia

  • Dita Aditianingsih, Professor · Faculty of Medicine, University of Indonesia

  • Arif HM Marsaban, MD · Faculty of Medicine, University of Indonesia

  • Gardian L Hakim, MD · Dharmais Cancer Hospital

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-01
Primary Completion
2024-11-30
Completion
2025-03-04

Countries

  • Indonesia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07144475 on ClinicalTrials.gov